Hemodynamic effects of urapidil, dilevalol and acebutolol in essential hypertension.

Cardiovascular effects of acebutolol and hydrochlorothiazide in essential hypertension.

During a double-blind crossover study of hydrochlorothiazide (HCT) and acebutolol (ACB), 11 patients 45 to 69 years old with essential hypertension underwent studies of forearm blood flow (FBF), arterial resistance (FAR), and venous compliance (FVC) using mercury-in-Silastic plethysmography. Placebo periods of 12 weeks were followed by a variable period of incremental doses of either active dru...

Benefit of Dilevalol in Hypertension

We compared dilevalol (an isomer of labetalol), 200-400 mg daily, against atenolol, 50-100 mg daily, in a double-blind, crossover, placebo-controlled trial with respect to effects on arterial distensibility (measured as pulse wave velocity [FVW]) and wave reflection (assessed from carotid pressure wave contour). Twelve patients of mean age 58 years (range 44-73 years) with essential hypertensio...

Hemodynamic Patterns in Essential Hypertension.

Systemic Hemodynamic Effects of Bethanidine in Essential Hypertension By STEVEN

Although available elsewhere, bethanidine remains under study in the U.S. and its hemodynamic effects are unreported. Therefore, 29 patients with moderately severe essential hypertension received one of four oral dose levels (0.10, 0.25, 0.35, or 0.50 mg/kg) of the postganglionic sympatholytic drug. Blood pressure was reduced only in the 14 patients receiving the highest dose. This was demonstr...

Systemic hemodynamic effects of bethanidine in essential hypertension.

Although available elsewhere, bethanidine remains under study in the U.S. and its hemodynamic effects are unreported. Therefore, 29 patients with moderately severe essential hypertension received one of four oral dose levels (0.10, 0.25, 0.35, or 0.50 mg/kg) of the postganglionic sympatholytic drug. Blood pressure was reduced only in the 14 patients receiving the highest dose. This was demonstr...